Shihuan Kuang
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Contact Information Email: skuang@purdue.edu Office: CRTN 2070 Map Phone: 765-494-8283 Homepage: Homepage |
Professor of Animal Sciences Cancer Center Chair in Stem Cell Biology  PubMed Listing  Google Scholar Listing  View Vita
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Pillars of Interdisciplinary Research Excellence
Enhancing Biological and Physical Function in Later Life; Engineering over the Life Course; Preserving Cognitive Function
Education
PhD University of Alberta Physiology and Cell Biology 2002
Research Interests
Stem cells in muscle health, obesity, and cancer
Teaching Interests
ANSC55500 (Animal Growth and Development - focusing on stem cells and development/regeneration)
Grants
2023 - NIH NIDDK R01
2023 - USDA NIFA
2021 - NIH NIAMS R01
2021 - Indiana Soybean Alliance
2021 - NIH NIAMS R01
2020 - NIH NIAMS
Selected Publications
Yue F, Oprescu SN, Qiu J, Gu L, Zhang L, Chen J, Narayanan N, Deng M, Kuang S. 2022. Lipid droplet dynamics regulate adult muscle stem cell fate. Cell Rep 38: 110267. IF: 9.9 https://doi.org/10.1016/j.celrep.2021.110267 Highlighted in F1000 Faculty Opinion
Yue F, Song C, Huang D, Narayanan N, Qiu J, Jia Z, Yuan Z, Oprescu SN, Roseguini BT, Deng M, Kuang S. 2021. Pten Inhibition Ameliorates Muscle Pathology and Function in a Mouse Model of Duchenne Muscular Dystrophy. Mol Ther, 29(1):132-48. IF: 12.9 https://doi.org/10.1016/j.ymthe.2020.09.029. Featured in: Parveen et al (2021) Mol Ther. https://doi.org/10.1016/j.ymthe.2020.12.014
Jia Z, Yue F, Chen X, Narayanan N, Qiu J, Syed SA, Imbalzano AN, Deng M, Yu P, Hu CD, Kuang S. 2020. Protein arginine methyltransferase PRMT5 regulates fatty acid metabolism and lipid droplet biogenesis in white adipose tissues. Adv Sci. 7(23): 2002602. https://doi.org/10.1002/advs.202002602 IF: 17.5
Huang D, Yue F, Qiu J, Deng M, Kuang S. 2020. Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle. Acta Biomater. 118:196-206. https://doi.org/10.1016/j.actbio.2020.10.009 IF: 10.6
Oprescu SN, Yue F, Qiu J, Brito LF, Kuang S. 2020. Temporal dynamics and heterogeneity of cell populations during skeletal muscle regeneration. iScience. 23:100993. IF: 6.1 https://doi.org/10.1016/j.isci.2020.100993.
Huang D, Deng M, Kuang S. 2019. Polymeric carriers for controlled drug delivery in obesity treatment. Trends Endocrinol Metab. 30 (12), 974-89. https://doi.org/10.1016/j.tem.2019.09.004 IF: 10.6
Jia Z, Nie Y, Yue F, Kong Y, Gu L, Gavin TP, Liu X, Kuang S. 2019. A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. eLife, 8:e47097. IF: 8.7 https://doi.org/10.7554/eLife.47097