June 3, 2024
In a proof-of-concept study, researchers at the National Institutes of Health (NIH) have developed an artificial intelligence (AI) tool that uses routine clinical data, such as that from a simple blood test, to predict whether someone’s cancer will respond to immune checkpoint inhibitors, a type of immunotherapy drug that helps immune cells kill cancer cells. The machine-learning model may help doctors determine if immunotherapy drugs are effective for treating a patient’s cancer. The study, published June 3, 2024, in Nature Cancer, was led by researchers at the National Cancer Institute’s (NCI) Center for Cancer Research and Memorial Sloan Kettering Cancer Center in New York. NCI is part of the National Institutes of Health.
NIH scientists develop AI tool to predict how cancer patients will respond to immunotherapy
May 14, 2024
Many people who are being treated for cancer experience symptoms of depression, pain, and fatigue. But scientists are still studying how best to manage these symptoms in people with cancer. One approach is to integrate the assessment and treatment of symptoms as a part of routine cancer care. With this approach, people who need support are offered weekly cognitive behavioral therapy sessions from a trained counselor and/or medicine for their symptoms provided by their medical teams. The strategy, called integrated screening and stepped collaborative care, has now shown promise in a large clinical trial involving people with different types and stages of cancer.
New Approach May Help People with Cancer Better Manage Depression, Pain, and Fatigue
May 7, 2024
In people's early- to mid-20s, they reach what is called peak bone mineral density, which is higher for men than it is for women, according to researchers. This peak is one of the main determinants of fracture risk later in life. After reaching this peak, a person's bone density remains roughly stable for a couple of decades. Then, when women enter the menopausal transition, they experience accelerated bone loss. Men also experience bone density decline as they age. Sleep patterns also evolve over time.
May 6, 2024
Study suggests more extensive screening method in the first trimester of pregnancy may improve detection of preeclampsia.
Personalized screening early in pregnancy may improve preeclampsia detection
May 3, 2024
In one of the first studies of its kind, UC Santa Barbara researchers have found that the immune status of postpartum mothers shifts with how she feeds her baby. Certain inflammatory proteins -- substances that are secreted as part of an immune response -- peak at different times of day, correlating with whether the mothers breastfeed, pump or formula-feed their babies.
A new mother's immune status varies with her feeding strategy
May 3, 2024
The placenta's response to infections from malaria, toxoplasmosis and listeria has been mapped in high resolution, possibly paving the way for new treatment options.
Source of pregnancy complications from infections revealed by placenta map
May 2, 2024
Consistent adherence to physical activity guidelines throughout middle-age is associated with a higher health-related quality of life in women, according to a new study.
May 1, 2024
Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for everyone.
When working out, males are programmed to burn more fat, while females recycle it--at least in rats
May 1, 2024
Researchers changed the composition of the gut microbiota in male mice through common antibiotics, inducing a condition called dysbiosis, and found that: - Mouse pups sired by a dysbiotic father show significantly lower birth weight, and have increased risk of growth disorders and postnatal mortality.
May 1, 2024
NFLM was associated with anxiety/vigilance, fatigue/pain, brain fog, sexual symptoms, and volatile mood symptoms. Recognizing symptoms associated with NFLM may allow for more accurate expectations and improve perimenopause care.
