July 15, 2024
The intracellular bacterial pathogen Legionella pneumophila modulates host cell functions by secreting multiple effectors with diverse biochemical activities. In particular, effectors of the SidE family interfere with host protein ubiquitination in a process that involves production of phosphoribosyl ubiquitin (PR-Ub).
Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms
July 15, 2024
With four patents under his belt, Joshua Alexander, associate professor in Purdue University’s Department of Speech, Language, and Hearing Sciences, is no stranger to entrepreneurship and innovation. When he was approached about becoming the College of Health and Human Sciences’ (HHS) Innovation and Entrepreneurship Fellow, he was eager to give back to the college through the role, which began on July 1.
HHS Innovation and Entrepreneurship fellow aims to boost research innovation in the College of Health and Human Sciences
July 11, 2024
The Office of Research has announced spring 2024 SPARK Program awards and NIH incentive funding, which honor faculty making significant global research impact.
SPARK funding awards spotlight large-scale interdisciplinary research excellence
July 9, 2024
You could talk to Tillmann Kubis for hours. His laid-back demeanor and desire for everyone to understand what he’s working on is so compelling, it almost feels like you too could have a grasp on quantum mechanics.
From eureka moments to industry impact: Tillmann Kubis’ quantum code library
July 9, 2024
Pasta without sauce. Unsalted crackers. Plain white rice. What is traditionally known to be the renal diet — a complicated diet with a wide range of restrictions, including limited protein, potassium, phosphorus and sodium — often lacks flavor and color, leaving individuals with chronic kidney disease (CKD) who have been prescribed the diet dissatisfied with their meal options. Some patients go as far as ignoring aspects of the diet altogether.
From bland to beneficial, Purdue nutrition science researcher explores diet as a tool for kidney disease prevention
June 25, 2024
Acute myeloid leukemia (AML) is a cancer of the bone marrow and the blood that progresses rapidly without treatment. The National Cancer Institute estimates 20,800 new cases of AML will be diagnosed in 2024, which would represent 1% of new cancer cases in the United States. It is most often diagnosed in people between the ages of 65 and 74, with a median age of 69. Although uncommon, AML can occur in children. The five-year relative survival rate is 31.9%. Now, researchers at Purdue University’s College of Science and collaborators have developed a patent-pending compound called HSN748 to treat drug-resistant AML.
Overcoming Drug-Resistant Acute Myeloid Leukemia with Engineered Compound
June 24, 2024
Purdue University researchers have unveiled biosensor technology aimed at transforming agricultural practices by swiftly identifying contamination risks in fresh produce.
Purdue researchers introduce biosensor technology for agriculture
June 24, 2024
Purdue University researchers in the College of Science have developed a patent-pending technology called RPOC, or real-time precision opto-control, which allows users to have site-specific and chemical-specific control of chemical processes within live cells.
Purdue technology provides site- and chemical-specific control of processes within live cells
June 24, 2024
Research to understand and quantify the effectiveness of a specific combination therapy against breast cancer has been singled out to receive the Purdue Women’s Global Health Institute’s 2024 Catherine Peachey Breast Cancer Research Program Award.
Promising breast cancer research receives WGHI’s Catherine Peachey grant
June 21, 2024
The number of women in STEM fields, including engineering, has increased in recent decades, paving the way for a brighter, more representative future in the U.S. International Women in Engineering Day spotlights these trailblazing women and their achievements in various engineering disciplines. Founded by the Women’s Engineering Society in the U.K., the day is now recognized across the world on June 23. The day has the broader aim of inspiring future generations of women engineers, fostering diversity and inclusivity in the field.
International Women in Engineering Day: Q&A with Kari Clase and Upinder Kaur