September 30, 2025
The three-dimensional structure provides essential information for understanding biological functions of proteins. To aid structure determination, computational prediction has been extensively studied. Despite significant progress, challenges remain on difficult targets, such as those with multiple domains and proteins that fold into several conformations.
Distance-AF improves predicted protein structure models by AlphaFold2 with user-specified distance constraints
September 29, 2025
Deep inside the brains of Alzheimer’s patients, immune cells are drowning in their own fat. This buildup of fat droplets inside brain immune cells helps explain why the brain loses its ability to fight off the disease and points toward a surprising new treatment that worked in mice within a week.
How Fat Build-Up In Brain Cells Opens Door For Alzheimer’s Disease
September 29, 2025
Acute respiratory distress syndrome (ARDS) is a lung inflammatory condition associated with the accumulation of fluid edema and cell infiltrates into the alveolar space along with dysregulation of the immune response.
Interleukin-27-adipose-derived mesenchymal stromal cell-based gene therapy attenuates inflammation in lipopolysaccharide-induced acute respiratory distress syndrome
September 26, 2025
The continually expanding toolkit from Mohit Verma’s laboratory at Purdue University now includes a portable paper-based biosensor for identifying genetically modified corn and soybean. The genetically modified crop biosensor, based on a method called loop-mediated isothermal amplification – LAMP – offers a fast and less expensive alternative to the point-of-need molecular tools already on the market.
September 26, 2025
A new edition of a time-tested and influential veterinary work is on the market thanks to the scholarly efforts of two Purdue Veterinary Medicine faculty members and their team of U.S. and international experts from multiple veterinary schools.
PVM Scholars Co-edit New Edition of Signature Veterinary Histology Textbook
September 25, 2025
Brain cells “clogged” with fat could be hidden drivers of Alzheimer’s disease, according to a new study that shifts focus away from protein plaques and tangles thought to be the main contributors behind the condition.
Discovery of hidden driver of Alzheimer’s could lead to new treatments, scientists say
September 22, 2025
Marxa Figueiredo, associate professor of basic medical sciences and the dean’s fellow for graduate programs in the College of Veterinary Medicine, and John Turek, professor emeritus, and their published book “Dellmann’s Textbook of Veterinary Histology.”
September 19, 2025
The continually expanding toolkit from Mohit Verma’s laboratory at Purdue University now includes a portable, paper-based biosensor for identifying genetically modified (GM) corn and soybean. The GM crop biosensor, based on a method called loop-mediated isothermal amplification (LAMP), offers a fast and less expensive alternative to the point-of-need molecular tools already on the market.
Novel Biosensor Detects Genetically Modified Corn and Soybean
September 19, 2025
One-carbon metabolism influences gene expression by providing methyl units for DNA, RNA, and histone methylation.
Drosophila Ahcy is a redox sensor that modulates gene expression to protect against light stress-induced retinal degeneration
September 18, 2025
Representatives from Purdue University’s College of Veterinary Medicine (PVM) and the Indiana Animal Disease Diagnostic Laboratory (ADDL) demonstrated their ongoing commitment to Indiana’s poultry industry by participating in the annual Indiana State Poultry Association (ISPA) Johndrew Memorial Golf Outing, held Wednesday, September 10, at The Fort Golf Course at Fort Harrison State Park in Indianapolis.
PVM and Indiana ADDL representatives connect with poultry industry
