November 9, 2022
Purdue researchers Jacqueline Linnes and Sulma Mohammed are determined to save lives by developing a low-cost, point-of-care paper test that could revolutionize cervical cancer detection worldwide, according to a news release from the university.
Purdue: Affordable cervical cancer test holds life-preserving promise
November 7, 2022
The seventh annual Distinguished and Named Professorship Ceremony on Thursday (Nov. 3) celebrated midcareer, distinguished, and named professors and administrators at Purdue for their accomplishments and successes.
Distinguished and Named Professorship Ceremony honors faculty, administrators
November 7, 2022
Tissue microarrays (TMAs) are commonly used for the rapid analysis of large numbers of tissue samples, often in morphological assessments but increasingly in spectroscopic analysis, where specific molecular markers are targeted via immunostaining. Here we report the use of an automated high-throughput system based on desorption electrospray ionization (DESI) mass spectrometry (MS) for the rapid generation and online analysis of high-density (6144 samples/array) TMAs, at rates better than 1 sample/second. Direct open-air analysis of tissue samples (hundreds of nanograms) not subjected to prior preparation, plus the ability to provide molecular characterization by tandem mass spectrometry (MS/MS), make this experiment versatile and applicable to both targeted and untargeted analysis in a label-free manner. These capabilities are demonstrated in a proof-of-concept study of frozen brain tissue biopsies where we showcase (i) a targeted MS/MS application aimed at identification of isocitrate dehydrogenase mutation in glioma samples and (ii) an untargeted MS tissue type classification using lipid profiles and correlation with tumor cell percentage estimates from histopathology.
November 4, 2022
Rescue Biomedical has received a Fast-Track Small Business Innovation Research, or SBIR, grant from the National Institutes of Health to develop its technology that detects when a person is overdosing on an opioid and delivers naloxone to reverse the action. Hyowon “Hugh” Lee, Rescue Biomedical CEO, said the company looks to partner with recovery clinics and clinicians to identify and work with opioid use disorder (OUD) patients at high risk of overdosing again. “OUD patients who recently undergo treatment are at a higher risk of accidentally overdosing again due to their lowered tolerance,” said Lee, who also is a Purdue University associate professor from the Weldon School of Biomedical Engineering, director of the Center for Implantable Devices at Purdue, and Purdue Faculty Champion in Mental Health and Substance Misuse. “Our device is a closed-loop drug delivery system that automatically detects when someone is overdosing and immediately provides life-saving naloxone to prevent long-term neurological damage or death.”
November 4, 2022
Purdue University and the Indian Institute of Technology Madras (IIT Madras) will soon launch a dual-degree master’s program in semiconductors as part of a newly signed agreement to cooperate in education and research in semiconductors and microelectronics. The proposed dual-degree program will be designed to ramp up skilled talent for the next generation of the semiconductor workforce. It will focus on an innovative, cooperatively developed curriculum to meet the industry’s growing needs. Undergraduate students with strong academic credentials and deep interest in working on topics related to semiconductor devices, chip fabrication, and circuits and systems will be candidates for the future master’s program.
Purdue partners with IIT Madras to create semiconductor dual-degree program
October 31, 2022
Funded research awards for September 2022 Swift TAB Investigator(s): Mary Johnson**; Sponsor: Federal Aviation Administration; Polytechnic: $7,670 Auto-flight Mode Confusion: Accidents and Incidents Investigator(s): Dimitrios Ziakkas**, Michael Suckow, Brian Dillman; Sponsor: Federal Aviation Administration; Polytechnic: $60,000; Total: $60,000 PEGASAS Management and Center Proposal Investigator(s): Mary Johnson, William Crossley**, Karen Marais; Sponsor: Federal Aviation Administration; Polytechnic: $9,075.50; Total: $119,913 Data Coordinating Center for the Alcoholic Hepatitis Research Network Investigator(s): Justin Yang**; Sponsor: Indiana University; Polytechnic: $53,966 Interactive Multi-Human Multi-Remote-Robot Operations for Future Construction Field Investigator(s): Jin Kocsis**, Jiansong Zhang, Dongming Gan, Mesut Akdere, BC Min; Sponsor: National Science Foundation; Polytechnic: $150,000 Sustainable Battery Electrode Manufacturing with High Active Material Loading Investigator(s): Sunghwan Lee**; Sponsor: National Science Foundation; Polytechnic: $50,000 The Science Gateways Community Institute (SGCI) for the Democratization and Acceleration of Science Investigator(s): Paul Parsons**; Sponsor: University of California-San Diego; Polytechnic: $56,040 Collaborative Robotics in NSF National I-corps Program Investigator(s): Dongming Gan**; Sponsor: National Science Foundation; Polytechnic: $50,000 Integration of Advanced Technologies for Documenting the Impact of Climate-Induced Stress on Whole Potato Plant Growth and Development Investigator(s): Suranjan Panigrahi**; Sponsor: Agricultural Research Service; Polytechnic: $19,000 **Indicates principal investigator Total Polytechnic awards = $299,711.50
October 28, 2022
Faculty and staff honors: Jacqueline Linnes, the Marta E. Gross Associate Professor of Biomedical Engineering and director of the College of Engineering Honors Program, and Peristera Paschou, professor of biological sciences and associate dean in the College of Science, have been selected for the Class of 2022-2023 of Drexel University’s Executive Leadership in Academic Technology, Engineering and Science (ELATES) program. ELATES is a national leadership development program designed to promote women in academic STEM fields and faculty allies of all genders into institutional leadership roles.
October 27, 2022
A made-in-Indiana business story—and one of the state’s first ventures in gene therapy—could save the lives of patients with a devastating brain tumor who typically have little over a year to live “if they’re lucky,” says one researcher. The development of a potential treatment for glioblastoma marks the first time in Indiana that every link in the chain is in place to commercialize the discovery: a university-based discovery, a startup to develop it—and for the first time—a young Hoosier manufacturer ready to make the cutting-edge gene therapy. Purdue University is the first chapter of the story, where Industrial and Physical Pharmacy Assistant Professor Dr. Sandro Matosevic discovered a potential therapy for glioblastoma, the most aggressive kind of brain tumor in which patients typically survive only 15 months. Matosevic says the need for a cure “is graver than a lot of other cancers, because there’s really no treatment.”
Purdue, Monon Bioventures, Genezen use $400K to team up against tumor
October 23, 2022
In an effort to help answer the fresh produce industry’s most urgent food safety questions, the Center for Produce Safety (CPS) is funding 14 new research projects, valued at more than $3.9 million. These 14 new projects are aimed at answering industry questions about leafy greens production in controlled environments, evaluating and mitigating risk from Listeria monocytogenes and Salmonella, and Cyclospora detection.
October 22, 2022
MSE Assistant Professor, Rahim Rahimi has created a process that immobilizes silver onto the implant surfaces of titanium orthopedic devices to improve antibacterial properties and cellular integration. This can help reduce infection when medical devices are implanted into people.
